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Why would a doctor suggest GlyNAC?

Every so often a customer tells us they started taking GlyNAC because their GP or a specialist suggested it. It has happened often enough now that we started paying attention, and it made us curious. Doctors are, quite rightly, cautious about supplements. So what is it about this one? We are not doctors and we […]

David Sinclair: what the most argued-about man in longevity science actually takes

If you have spent any time reading about healthy ageing, you have come across David Sinclair. The Harvard geneticist wrote the bestseller Lifespan, runs a leading ageing research laboratory, and did more than anyone to bring NMN and resveratrol into the public conversation. He is also one of the most criticised figures in longevity science. […]

NMN vs NR: The First Head-to-Head Human Trial Has Results

Diagram of NMN and NR being converted by gut bacteria into nicotinic acid, which raises blood NAD+

In short: in the first direct human comparison (Nature Metabolism, January 2026), NMN and NR raised blood NAD+ to a similar degree, roughly doubling levels after 14 days of daily use. Plain vitamin B3 did not produce a lasting increase. The study measured NAD+ levels, not health outcomes. Since we started this business in 2020, […]

Spermidine: what the research actually shows

Spermidine has been on our list of “things to look into properly” for about two years. It kept coming up in the healthy ageing literature, and a number of you have emailed asking about it. We have now finished the work and added it to the range, so here is what we found. This is […]

Resveratrol, Your Gut, and Insulin Sensitivity: What a New Human Study Found

Most resveratrol research is done in mice. This one was done in people. A study published in the European Journal of Nutrition in December 2025 looked at three things at once: insulin sensitivity, blood fats, and the gut microbiome. It is small and short, with clear limits set out below, but it is a human […]

NMN and Sleep: New Research Reveals a Surprising Brain Connection

Introduction If you’ve noticed that sleep feels less restorative as you get older, that you wake more easily, dream less vividly, or simply don’t feel as refreshed in the morning, you’re not alone and you’re not imagining it. REM sleep, the phase associated with dreaming, emotional processing, and memory consolidation, declines meaningfully with age. Researchers […]

Can NMN Improve Physical Performance? A Human Trial Worth Knowing About

One of the most common questions we get at MyVitality is some version of: “The mouse studies are interesting, but what does NMN actually do in real humans?” It’s a fair question. Animal research has long shown that NMN can boost NAD+ levels and slow age-related decline in rodents, but the picture in humans has […]

New NR study explores NAD+, circadian rhythm and cardiac ageing

NAD+, circadian rhythm and cardiac ageing study

A newly published preclinical study in Communications Biology adds to the growing scientific interest in NAD+ and healthy ageing. The paper, titled “NAD+ controls circadian rhythmicity during cardiac aging”, looked at how age-related declines in cardiac NAD+ may affect the heart’s internal daily rhythms, and whether NAD+ precursor supplementation could help restore some of those […]

NMN and Heart Ageing: What a New Study Found

NMN and Heart Ageing Study

A newly published study has added another interesting data point to the growing body of NMN research. In this 2026 preclinical study, researchers investigated whether nicotinamide mononucleotide (NMN) could help reduce signs of cardiac ageing and heart tissue damage in older mice fed a high-fat diet. You can view the published study HERE. The authors […]

New Study Explores NMN and Hair Quality

Introduction A recently published study has examined whether supplementation with nicotinamide mononucleotide (NMN) may influence aspects of hair quality. NMN has been widely studied for its role in supporting NAD+ levels and cellular energy metabolism, processes that are important in many areas of healthy ageing. While NMN is most widely studied for its role in […]

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